FACULTY OF Chemistry

PROF. DR. NILS METZLER-NOLTE, CHAIR FOR BIOINORGANIC CHEMISTRY

Research in the Metzler-Nolte group is focused on the use of cold, atmospheric-pressure plasmas for chemical reac-tions and biological studies. By employing a range of analytical techniques, the group has elucidated the plasma reaction products of important biomolecules such as glutathione and vitamin B12, and selenium-containing bio-molecules. Moreover, we have described the interplay of redox-active transition metal ions such as iron with cold plasma, demonstrating catalytic reactions with plasmas. Current investigations use cold plasma to activate bio-active molecules and study the synergistic effects of cytotoxic molecules and plasmas, thereby potentially offering new approaches towards the treatment of neurodegenerative diseases or cancer.

Keywords: Plasma, plasma chemistry, medicinal chemistry, drug research, reactive oxygen species (ROS)

Webpage: Bioinorganic Chemistry